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Alogliptin

Brand names: INCRESYNC (in combination) KAZANO (in combination) NESINA OSENI (in combination) VIPDOMET (in combination) VIPIDIA

Description

Alogliptin is a potent and highly selective inhibitor of DPP-4, >10,000-fold more selective for DPP-4 than other related enzymes including DPP-8 and DPP-9. Alogliptin improves glycaemic control via a glucose-dependent mechanism, whereby insulin release is enhanced and glucagon levels are suppressed when glucose levels are high.

ATC Classification

Code
Title
Category
A10BH04
Alogliptin
A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BH Dipeptidyl peptidase 4 (DPP-4) inhibitors

Related medicines

MPI, EU: SmPC 2018: VIPIDIA Film-coated tablets
MPI, US: SPL/PLR 2019: NESINA Film-coated tablet

2D Molecule Structure

Unique Ingredient Identifier (UNII)

JHC049LO86 - ALOGLIPTIN

CAS Registry Number

850649-61-5 - alogliptin

SNOMED-CT

702799001 - Alogliptin (substance)

 
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