Alogliptin
Chemical formula: C₁₈H₂₁N₅O₂ Molecular mass: 339.392 g/mol PubChem compound: 11450633
Active ingredient description
Alogliptin is a potent and highly selective inhibitor of DPP-4, >10,000-fold more selective for DPP-4 than other related enzymes including DPP-8 and DPP-9. Alogliptin improves glycaemic control via a glucose-dependent mechanism, whereby insulin release is enhanced and glucagon levels are suppressed when glucose levels are high.
Medicine classification
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| A10BH04 | A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BH Dipeptidyl peptidase 4 (DPP-4) inhibitors | |
Product monographs
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| NESINA Film-coated tablet | FDA, National Drug Code (US) | MPI, US: SPL/PLR | |
| VIPIDIA Film-coated tablet | European Medicines Agency (EU) | MPI, EU: SmPC |
Medicines
Alogliptin is an active ingredient of these brands:
United States (US)Australia (AU)
Brazil (BR)
Hong Kong (HK)
Japan (JP)Mexico (MX)
Singapore (SG)
Turkey (TR)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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