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Alogliptin

Description

Alogliptin is a potent and highly selective inhibitor of DPP-4, >10,000-fold more selective for DPP-4 than other related enzymes including DPP-8 and DPP-9. Alogliptin improves glycaemic control via a glucose-dependent mechanism, whereby insulin release is enhanced and glucagon levels are suppressed when glucose levels are high.

ATC Classification

Code
Title
Category
A10BH04
Alogliptin
A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BH Dipeptidyl peptidase 4 (DPP-4) inhibitors

Trade names

Trade name
Countries
NESINA

Australia Canada Singapore United States

VIPIDIA

Austria

Trade names (in combination): INCRESYNC KAZANO NESINA MET OSENI VIPDOMET

Product Monographs

Monograph
Type
Country
VIPIDIA Film-coated tablets
MPI, EU: SmPC
NESINA Film-coated tablet
MPI, US: SPL/PLR
US

2D Molecule Structure

Unique Ingredient Identifier (UNII)

JHC049LO86 - ALOGLIPTIN

CAS Registry Number

850649-61-5 - alogliptin

SNOMED-CT

702799001 - Alogliptin (substance)

 
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