Alogliptin C₁₈H₂₁N₅O₂

Active ingredient description

Alogliptin is a potent and highly selective inhibitor of DPP-4, >10,000-fold more selective for DPP-4 than other related enzymes including DPP-8 and DPP-9. Alogliptin improves glycaemic control via a glucose-dependent mechanism, whereby insulin release is enhanced and glucagon levels are suppressed when glucose levels are high.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BH Dipeptidyl peptidase 4 (DPP-4) inhibitors
Discover more medicines within A10BH04

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
European Medicines Agency (EU)
Summary of Product Characteristics (SPC)
FDA, National Drug Code (US)
Structured Product Labeling (SPL/PLR)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₈H₂₁N₅O₂
Molecular mass: 339.392 g/mol

External identifiers

CAS Substance: 850649-61-5
DrugBank Drug: DB06203
KEGG Drug: D06553
PubChem Compound: 11450633
RxNorm Ingredient: 1368001
SNOMED-CT Concept: 702799001
Alogliptin (substance)
UNII Identifier: JHC049LO86
ALOGLIPTIN

Medicines

Alogliptin is an active ingredient of these brands:

United States (US)

  • NESINA as ALOGLIPTIN BENZOATE

  • (combination) KAZANO as ALOGLIPTIN BENZOATE
  • (combination) OSENI as ALOGLIPTIN BENZOATE

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

  • NESINA as ALOGLIPTIN BENZOATE

  • (combination) KAZANO as ALOGLIPTIN BENZOATE

Ecuador (EC)

  • FEBUDAN as ALOGLIPTIN BENZOATE

  • (combination) FEBUMET as ALOGLIPTIN BENZOATE

Estonia (EE)

Finland (FI)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

  • NESINA as ALOGLIPTIN BENZOATE

  • (combination) INISYNC as ALOGLIPTIN BENZOATE
  • (combination) LIOVEL as ALOGLIPTIN BENZOATE

Lithuania (LT)

Mexico (MX)

Poland (PL)

Singapore (SG)

  • NESINA as ALOGLIPTIN BENZOATE

Spain (ES)

Turkey (TR)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

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