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Alteplase

Also known as: t-PA t-plasminogen activator Tissue-type plasminogen activator precursor tPA

Brand names: ACTILYSE ACTIVASE RT-PA CATHFLO

Description

Alteplase is a recombinant human tissue-type plasminogen activator, a glycoprotein, which activates plasminogen directly to plasmin. Once bound to fibrin, it is activated, inducing the conversion of plasminogen to plasmin leading to the dissolution of the fibrin clot.

ATC Classification

Code
Title
Category
B01AD02
Alteplase
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AD Enzymes
S01XA13
Alteplase
S Sensory organs → S01 Ophthalmologicals → S01X Other ophthalmologicals → S01XA Other ophthalmologicals

Related medicines

MPI, US: SPL/Old 2020: CATHFLO ACTIVASE Powder for solution for injection
MPI, EU: SmPC 2018: ACTILYSE Powder and solvent for solution

3D Molecule Structure

Unique Ingredient Identifier (UNII)

1RXS4UE564 - ALTEPLASE

CAS Registry Number

105857-23-6 - alteplase

SNOMED-CT

387152000 - Alteplase (substance)

 
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