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Alteplase

Also known as: t-PA t-plasminogen activator Tissue-type plasminogen activator precursor tPA

Description

Alteplase is a recombinant human tissue-type plasminogen activator, a glycoprotein, which activates plasminogen directly to plasmin. Once bound to fibrin, it is activated, inducing the conversion of plasminogen to plasmin leading to the dissolution of the fibrin clot.

ATC Classification

Code
Title
Category
B01AD02
Alteplase
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AD Enzymes
S01XA13
Alteplase
S Sensory organs → S01 Ophthalmologicals → S01X Other ophthalmologicals → S01XA Other ophthalmologicals

Trade names

Trade name
Countries
ACTILYSE

Austria Cyprus France Netherlands Singapore

ACTIVASE RT-PA

Canada

CATHFLO

Canada United States

Product Monographs

Monograph
Type
Country
ACTILYSE Powder and solvent for solution
MPI, EU: SmPC
UK
CATHFLO ACTIVASE Powder for solution for injection
MPI, US: SPL/Old
US

3D Molecule Structure

Unique Ingredient Identifier (UNII)

1RXS4UE564 - ALTEPLASE

CAS Registry Number

105857-23-6 - alteplase

SNOMED-CT

387152000 - Alteplase (substance)

 
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