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Amantadine

Also known as: 1-aminoadamantane Amantadine Amantadine hydrochloride

Description

Amantadine has been shown to be a low affinity antagonist at the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors. Overactivity of glutamatergic neurotransmission has been implicated in the generation of parkinsonian symptoms. In addition, amantadine specifically inhibits the replication of influenza A viruses at low concentrations.

ATC Classification

Code
Title
Category
N04BB01
Amantadine
N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BB Adamantane derivatives

Trade names

Trade name
Countries

United States

United States

Austria

Australia Netherlands Singapore

Product Monographs

Monograph
Type
Country
TRILASYM Oral solution
MPI, EU: SmPC
UK