Amantadine

Also known as: 1-aminoadamantane Amantadine Amantadine hydrochloride

Active ingredient description

Amantadine has been shown to be a low affinity antagonist at the N-methyl-D-aspartate (NMDA) subtype of glutamate receptors. Overactivity of glutamatergic neurotransmission has been implicated in the generation of parkinsonian symptoms. In addition, amantadine specifically inhibits the replication of influenza A viruses at low concentrations.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Amantadine
N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BB Adamantane derivatives
Discover more medicines within N04BB01

Medicines

Amantadine is the active ingredient of these drugs:

Drug
Countries

Hong Kong

Tunisia

Poland

Hong Kong

United States

France

Brazil

United States

Austria Hong Kong Lithuania

Australia Hong Kong Netherlands New Zealand Singapore

Poland

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

BF4C9Z1J53 - AMANTADINE

CAS registry number

665-66-7 - 1-Adamantanamine, hydrochloride

768-94-5 - amantadine

SNOMED-CT

372763006 - Amantadine (substance)