Ambroxol

Active ingredient description

Ambroxol induces activation of the surfactant system by acting directly on the type II pneumocytes of the alveoles and the Clara cells in the region of the small airways. It promotes the formation and outward transfer of surface-active material in the alveolar and bronchial region of the foetal and adult lungs.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
R Respiratory system → R02 Throat preparations → R02A Throat preparations → R02AD Anesthetics, local
Discover more medicines within R02AD05
Ambroxol
R Respiratory system → R05 Cough and cold preparations → R05C Expectorants, excl. combinations with cough suppressants → R05CB Mucolytics
Discover more medicines within R05CB06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)

Medicines

Ambroxol is the active ingredient of these drugs:

Drug
Countries

Tunisia

Poland

Ecuador

Estonia Lithuania

Austria

Germany

Tunisia

Austria Germany Poland

Brazil

Austria Estonia Lithuania

Estonia Poland

Hong Kong

Lithuania Poland

Lithuania

Lithuania

Brazil

Hong Kong

Hong Kong

Hong Kong

Hong Kong

Hong Kong Singapore

Spain

Hong Kong

Hong Kong Mexico Singapore

Ecuador

Ecuador

Brazil

Estonia Lithuania

Brazil

Lithuania

Ecuador

Spain

Ecuador

Poland

Spain

Poland

Poland

Hong Kong

Brazil Ecuador

Estonia Finland Lithuania Poland

Brazil Cyprus

Brazil

Hong Kong

Poland

Poland

Lithuania

Cyprus

Estonia Lithuania

Hong Kong

Cyprus

Cyprus Hong Kong

Ecuador

Spain

Hong Kong

Hong Kong

Spain

Austria Ecuador Germany Mexico Netherlands

Hong Kong

Cyprus

Ecuador

Singapore

Hong Kong

Brazil

Austria Spain

Austria Brazil Cyprus Ecuador Germany

Brazil

Ecuador

Brazil

Brazil

Spain

Ecuador France Tunisia

Hong Kong

Poland

Estonia Lithuania

Ecuador

Brazil

Poland

Singapore

Estonia

Brazil

Hong Kong

Brazil

Singapore

Brazil

Hong Kong Singapore

France Tunisia

Hong Kong

Ecuador

Hong Kong

Ambroxol is also found within below combination drugs:

AERO EXPECTUSS , ALIVID , ASCORIL LS , BEMIN FLUX , BROGAMAX , BRONCOVITAL , BROSOL , BROXOL PLUS , BROXOLAM COMPUESTO , CLARIXOL , CLEMBROXIL , CORICIDIN EXPEC , EXPECTUSS ALER , FLUPULMIN , FLUSAM PLUS , HISTIACIL NF , LOBRAXOL , LORAMBROX , MUCOSOLVAN COMPOSITUM , MUCOSPAS , MUCOXIN JUNIOR , MUCOXIN RELAX , NEBULASMA PLUS , REZPLEN

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₃H₁₈Br₂N₂O
Molecular mass: 378.108 g/mol

External identifiers

CAS Substance: 18683-91-5
DrugBank Drug: DB06742
KEGG Drug: D07442
PubChem Compound: 2132
RxNorm Ingredient: 625
SNOMED-CT Concept: 698024002
Ambroxol (substance)
UNII Identifier: 200168S0CL
AMBROXOL