Amorolfine

Chemical formula: C₂₁H₃₅NO Molecular mass: 317.517 g/mol PubChem compound: 54260

Active ingredient description

Amorolfine is a broad spectrum antimycotic. Amorolfine belongs to a new chemical class, and its fungicidal action is based on an alteration of the fungal cell membrane targeted primarily on sterol biosynthesis. The ergosterol content is reduced, and at the same time unusual sterically nonplanar sterols accumulate.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group		Classification
D01AE16	Amorolfine	D Dermatologicals → D01 Antifungals for dermatological use → D01A Antifungals for topical use → D01AE Other antifungals for topical use
Discover more medicines within D01AE16

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document	Type	Information Source
LOCERYL Nail lacquer	MPI, EU: SmPC	Medicines & Healthcare Products Regulatory Agency (GB)

Medicines

Amorolfine is an active ingredient of these brands:

Australia (AU)

APORYL
LOCERYL as AMOROLFINE HYDROCHLORIDE
MYCONAIL

Austria (AT)

AMOROCUTAN as AMOROLFINE HYDROCHLORIDE
EXOROLFIN as AMOROLFINE HYDROCHLORIDE
LOCERYL as AMOROLFINE HYDROCHLORIDE

Brazil (BR)

DERMOCERYL as AMOROLFINE HYDROCHLORIDE
LOCERYL as AMOROLFINE HYDROCHLORIDE
LOMYTRAT as AMOROLFINE HYDROCHLORIDE
ONICORYL as AMOROLFINE HYDROCHLORIDE
ONIMORF as AMOROLFINE HYDROCHLORIDE
UNHA SANA as AMOROLFINE HYDROCHLORIDE

Croatia (HR)

AMOFIN as AMOROLFINE HYDROCHLORIDE
ARIVIL as AMOROLFINE HYDROCHLORIDE
FUNGILAC as AMOROLFINE HYDROCHLORIDE

Cyprus (CY)

LOCERYL as AMOROLFINE HYDROCHLORIDE

Ecuador (EC)

LOCERYL as AMOROLFINE HYDROCHLORIDE

Estonia (EE)

EXOLORFIN
LOCERYL as AMOROLFINE HYDROCHLORIDE

Finland (FI)

LOCERYL as AMOROLFINE HYDROCHLORIDE

France (FR)

LOCERYL as AMOROLFINE HYDROCHLORIDE

Hong Kong (HK)

ALIKANG as AMOROLFINE HYDROCHLORIDE
CURAFEN as AMOROLFINE HYDROCHLORIDE
CURANAIL as AMOROLFINE HYDROCHLORIDE
LOCERYL as AMOROLFINE HYDROCHLORIDE
LOMORYL as AMOROLFINE HYDROCHLORIDE
ROMARYL as AMOROLFINE HYDROCHLORIDE
YEESLOK as AMOROLFINE HYDROCHLORIDE

Ireland (IE)

CURANAIL as AMOROLFINE HYDROCHLORIDE
LOCERYL as AMOROLFINE HYDROCHLORIDE
SCHOLLMED as AMOROLFINE HYDROCHLORIDE

Israel (IL)

FUNGOFIN as AMOROLFINE HYDROCHLORIDE
LOCERYL as AMOROLFINE HYDROCHLORIDE

Japan (JP)

PEKIRON as AMOROLFINE HYDROCHLORIDE

Lithuania (LT)

EXOLORFIN
FUNTROL as AMOROLFINE HYDROCHLORIDE
GIFUGAN as AMOROLFINE HYDROCHLORIDE
LOCERYL as AMOROLFINE HYDROCHLORIDE

Malta (MT)

LOCERYL as AMOROLFINE HYDROCHLORIDE

New Zealand (NZ)

LOCERYL as AMOROLFINE HYDROCHLORIDE
MYCONAIL
ONYBAN as AMOROLFINE HYDROCHLORIDE
REPARO as AMOROLFINE HYDROCHLORIDE

Poland (PL)

AMOROLAK as AMOROLFINE HYDROCHLORIDE
FUNTROL as AMOROLFINE HYDROCHLORIDE
LOCERYL as AMOROLFINE HYDROCHLORIDE
MYCONOLAK as AMOROLFINE HYDROCHLORIDE

Romania (RO)

EXODERIL SET as AMOROLFINE HYDROCHLORIDE

Singapore (SG)

LOCERYL as AMOROLFINE HYDROCHLORIDE

South Africa (ZA)

LOCERYL as AMOROLFINE HYDROCHLORIDE
NACLER as AMOROLFINE HYDROCHLORIDE
ONYBAN as AMOROLFINE HYDROCHLORIDE

Spain (ES)

LOCETAR as AMOROLFINE HYDROCHLORIDE
ODENIL as AMOROLFINE HYDROCHLORIDE

Tunisia (TN)

LOCERYL as AMOROLFINE HYDROCHLORIDE

Turkey (TR)

LOCERYL as AMOROLFINE HYDROCHLORIDE
ONIKOM as AMOROLFINE HYDROCHLORIDE

United Kingdom (UK)

LOCERYL as AMOROLFINE HYDROCHLORIDE
OMICUR as AMOROLFINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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