Amorolfine

Active ingredient description

Amorolfine is a broad spectrum antimycotic. Amorolfine belongs to a new chemical class, and its fungicidal action is based on an alteration of the fungal cell membrane targeted primarily on sterol biosynthesis. The ergosterol content is reduced, and at the same time unusual sterically nonplanar sterols accumulate.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Amorolfine
D Dermatologicals → D01 Antifungals for dermatological use → D01A Antifungals for topical use → D01AE Other antifungals for topical use
Discover more medicines within D01AE16

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Medicines

Amorolfine is the active ingredient of these drugs:

Drug
Countries

Hong Kong

Austria

Poland

Australia

Hong Kong

Hong Kong Ireland

Brazil

Romania

Estonia Lithuania

Austria

Lithuania Poland

Lithuania

Australia Austria Brazil Cyprus Ecuador

Spain

Hong Kong

Brazil

Australia New Zealand

Poland

South Africa

Spain

United Kingdom

Brazil

Turkey

Brazil

New Zealand South Africa

New Zealand

Hong Kong

Ireland

Brazil

Hong Kong

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₁H₃₅NO
Molecular mass: 317.517 g/mol

External identifiers

CAS Substance: 78613-35-1
DrugBank Drug: DB09056
PubChem Compound: 54260
RxNorm Ingredient: 17804
SNOMED-CT Concept: 391769002
Amorolfine (substance)
UNII Identifier: AB0BHP2FH0
AMOROLFINE