Chemical formula: C₂₁H₃₅NO Molecular mass: 317.517 g/mol PubChem compound: 54260
Amorolfine is a broad spectrum antimycotic. Amorolfine belongs to a new chemical class, and its fungicidal action is based on an alteration of the fungal cell membrane targeted primarily on sterol biosynthesis. The ergosterol content is reduced, and at the same time unusual sterically nonplanar sterols accumulate.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D01AE16 | Amorolfine | D Dermatologicals → D01 Antifungals for dermatological use → D01A Antifungals for topical use → D01AE Other antifungals for topical use |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| LOCERYL Nail lacquer | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Amorolfine is an active ingredient of these brands:
Austria (AT)
Brazil (BR)Croatia (HR)Cyprus (CY)
Ecuador (EC)
Finland (FI)
France (FR)
Hong Kong (HK)Ireland (IE)Japan (JP)
Lithuania (LT)Malta (MT)
New Zealand (NZ)Poland (PL)Romania (RO)
Singapore (SG)
South Africa (ZA)Tunisia (TN)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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