Amorolfine C₂₁H₃₅NO

Active ingredient description

Amorolfine is a broad spectrum antimycotic. Amorolfine belongs to a new chemical class, and its fungicidal action is based on an alteration of the fungal cell membrane targeted primarily on sterol biosynthesis. The ergosterol content is reduced, and at the same time unusual sterically nonplanar sterols accumulate.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
D01AE16
Amorolfine
D Dermatologicals → D01 Antifungals for dermatological use → D01A Antifungals for topical use → D01AE Other antifungals for topical use
Discover more medicines within D01AE16

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
LOCERYL Nail lacquer
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₁H₃₅NO
Molecular mass: 317.517 g/mol

External identifiers

CAS Substance: 78613-35-1
DrugBank Drug: DB09056
PubChem Compound: 54260
RxNorm Ingredient: 17804
SNOMED-CT Concept: 391769002
Amorolfine (substance)
UNII Identifier: AB0BHP2FH0
AMOROLFINE

Medicines

Amorolfine is an active ingredient of these brands:

Australia (AU)

Austria (AT)

Brazil (BR)

Cyprus (CY)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE

Ecuador (EC)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE

Estonia (EE)

Finland (FI)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE

France (FR)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE

Hong Kong (HK)

  • ALIKANG as AMOROLFINE HYDROCHLORIDE
  • CURAFEN as AMOROLFINE HYDROCHLORIDE
  • CURANAIL as AMOROLFINE HYDROCHLORIDE
  • LOCERYL as AMOROLFINE HYDROCHLORIDE
  • LOMORYL as AMOROLFINE HYDROCHLORIDE
  • ROMARYL as AMOROLFINE HYDROCHLORIDE
  • YEESLOK as AMOROLFINE HYDROCHLORIDE

Ireland (IE)

Japan (JP)

  • PEKIRON as AMOROLFINE HYDROCHLORIDE

Lithuania (LT)

Malta (MT)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE

New Zealand (NZ)

Poland (PL)

Romania (RO)

Singapore (SG)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE

South Africa (ZA)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE
  • NACLER as AMOROLFINE HYDROCHLORIDE
  • ONYBAN as AMOROLFINE HYDROCHLORIDE

Spain (ES)

  • LOCETAR as AMOROLFINE HYDROCHLORIDE
  • ODENIL as AMOROLFINE HYDROCHLORIDE

Tunisia (TN)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE

Turkey (TR)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE
  • ONIKOM as AMOROLFINE HYDROCHLORIDE

United Kingdom (UK)

  • LOCERYL as AMOROLFINE HYDROCHLORIDE
  • OMICUR as AMOROLFINE HYDROCHLORIDE

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

 
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