Active ingredient description

Amprenavir is a competitive inhibitor of HIV-1 protease. Amprenavir binds to the active site of HIV-1 protease and thereby prevents the processing of viral gag and gag-pol polyprotein precursors, resulting in the formation of immature non-infectious viral particles.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AE Protease inhibitors
Discover more medicines within J05AE05

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₅H₃₅N₃O₆S
Molecular mass: 505.627 g/mol

External identifiers

CAS Substance: 161814-49-9
DrugBank Drug: DB00701
KEGG Drug: D00894
PubChem Compound: 65016
RxNorm Ingredient: 228656
SNOMED-CT Concept: 387006009
Amprenavir (substance)
UNII Identifier: 5S0W860XNR