Anakinra

Therapeutic indications

Anakinra is indicated for:

Rheumatoid arthritis (RA)

Population group: both men and women, only adults (18 years old or older)

Anakinra is indicated in adults for the treatment of the signs and symptoms of RA in combination with methotrexate, with an inadequate response to methotrexate alone.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Treatment 1: Subcutaneous - 100 mg once a day

Cryopyrin-Associated Periodic Syndromes (CAPS)

Population group: both men and women, only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Anakinra is indicated in adults, adolescents, children and infants aged 8 months and older with a body weight of 10 kg or above for the treatment of CAPS, including:

  • Neonatal-Onset Multisystem Inflammatory Disease (NOMID) / Chronic Infantile Neurological, Cutaneous, Articular Syndrome (CINCA)
  • Muckle-Wells Syndrome (MWS)
  • Familial Cold Autoinflammatory Syndrome (FCAS)

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Treatment 1: Subcutaneous - 1-8 mg/kg once a day

Still's Disease

Population group: both men and women, only adults (18 years old or older)

Anakinra is indicated in adults, adolescents, children and infants aged 8 months and older with a body weight of 10 kg or above for the treatment of Still’s disease, including Systemic Juvenile Idiopathic Arthritis (SJIA) and Adult-Onset Still’s Disease (AOSD), with active systemic features of moderate to high disease activity, or in patients with continued disease activity after treatment with non-steroidal anti-inflammatory drugs (NSAIDs) or glucocorticoids.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Treatment 1: Subcutaneous - 1-4 mg/kg once a day

Contraindications

Anakinra is contraindicated in the following cases:

Neutropenia

Neutropenia

Medication Recommendation

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