Anastrozole

Active ingredient description

Anastrozole is a potent and highly selective non-steroidal aromatase inhibitor. It inhibits the enzyme aromatase, which is responsible for converting androgens to estrogens. Anastrozole is a drug indicated in the treatment of breast cancer in post-menopausal women.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Anastrozole
L Antineoplastic and immunomodulating agents → L02 Endocrine therapy → L02B Hormone antagonists and related agents → L02BG Aromatase inhibitors
Discover more medicines within L02BG03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Medicines

Anastrozole is the active ingredient of these drugs:

Drug
Countries

South Africa

Italy

Ireland

Spain

Ireland

Germany

South Africa

New Zealand

South Africa

South Africa

Finland

Tunisia

Tunisia

Germany

Australia

Austria

Brazil

Germany

Ecuador

Ecuador

New Zealand

Finland

Singapore

Singapore

Hong Kong

Italy

Brazil

Hong Kong Singapore

Brazil

Cyprus Hong Kong New Zealand Singapore

Australia

Australia Austria Brazil Canada Cyprus

Singapore

Poland

Tunisia

Estonia Lithuania

South Africa

South Africa

South Africa

Poland

South Africa

Italy

Hong Kong Singapore

Italy

South Africa

Italy

Italy

New Zealand

South Africa

Cyprus

Cyprus

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₁₇H₁₉N₅
Molecular mass: 293.366 g/mol

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 120511-73-1
DrugBank Drug: DB01217
KEGG Drug: D00960
PubChem Compound: 2187
RxNorm Ingredient: 84857
SNOMED-CT Concept: 386910003
Anastrozole (substance)
UNII Identifier: 2Z07MYW1AZ
ANASTROZOLE