Chemical formula: C₁₇H₁₇NO₂ Molecular mass: 267.322 g/mol PubChem compound: 6005
Apomorphine is a direct stimulant of dopamine receptors and while possessing both D1 and D2 receptor agonist properties does not share transport or metabolic pathways with levodopa. Its actions on parkinsonian motor disability are likely to be mediated at post-synaptic receptor sites.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| G04BE07 | Apomorphine | G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BE Drugs used in erectile dysfunction |
| N04BC07 | Apomorphine | N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BC Dopamine agonists |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| APO-GO Solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| KYNMOBI Sublingual film | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Apomorphine is an active ingredient of these brands:
Cyprus (CY)
France (FR)
Israel (IL)
Japan (JP)
Malta (MT)
New Zealand (NZ)
Poland (PL)
South Africa (ZA)
Tunisia (TN)
Turkey (TR)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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