Apomorphine

Chemical formula: C₁₇H₁₇NO₂  Molecular mass: 267.322 g/mol  PubChem compound: 6005

Active ingredient description

Apomorphine is a direct stimulant of dopamine receptors and while possessing both D1 and D2 receptor agonist properties does not share transport or metabolic pathways with levodopa. Its actions on parkinsonian motor disability are likely to be mediated at post-synaptic receptor sites.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
G04BE07 Apomorphine G Genito urinary system and sex hormones → G04 Urologicals → G04B Other urologicals, incl. antispasmodics → G04BE Drugs used in erectile dysfunction
Discover more medicines within G04BE07
N04BC07 Apomorphine N Nervous system → N04 Anti-parkinson drugs → N04B Dopaminergic agents → N04BC Dopamine agonists
Discover more medicines within N04BC07

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 KYNMOBI Sublingual film MPI, US: SPL/PLR FDA, National Drug Code (US)
 APO-GO Solution for injection MPI, EU: SmPC Medicines & Healthcare Products Regulatory Agency (GB)

Structural formula

Graphic representation of the active ingredient's molecular structure

3D molecular structure

3D representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 41372-20-7
CAS Substance: 58-00-4
DrugBank Drug: DB00714
KEGG Drug: D02004
PubChem Compound: 6005
RxNorm Ingredient: 1043
SNOMED-CT Concept: 387375001
Apomorphine (substance)
UNII Identifier: N21FAR7B4S
APOMORPHINE

Medicines

Apomorphine is an active ingredient of these brands:

Australia (AU)

  • APOMINE as APOMORPHINE HYDROCHLORIDE
  • MOVAPO as APOMORPHINE HYDROCHLORIDE

Austria (AT)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • DACEPTON as APOMORPHINE HYDROCHLORIDE

Canada (CA)

  • KYNMOBI as APOMORPHINE HYDROCHLORIDE
  • MOVAPO as APOMORPHINE HYDROCHLORIDE

Cyprus (CY)

  • APO-GO as APOMORPHINE HYDROCHLORIDE

Estonia (EE)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • DACEPTON as APOMORPHINE HYDROCHLORIDE

Finland (FI)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • DACEPTON as APOMORPHINE HYDROCHLORIDE

France (FR)

Ireland (IE)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • DACEPTON as APOMORPHINE HYDROCHLORIDE

Israel (IL)

  • APO-GO as APOMORPHINE HYDROCHLORIDE

Japan (JP)

  • APOKYN as APOMORPHINE HYDROCHLORIDE

Lithuania (LT)

Malta (MT)

  • APO-GO as APOMORPHINE HYDROCHLORIDE

Netherlands (NL)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • DACEPTON as APOMORPHINE HYDROCHLORIDE

New Zealand (NZ)

  • MOVAPO as APOMORPHINE HYDROCHLORIDE

Poland (PL)

Romania (RO)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • DACEPTON as APOMORPHINE HYDROCHLORIDE

South Africa (ZA)

  • UPRIMA as APOMORPHINE HYDROCHLORIDE

Spain (ES)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • DACEPTON as APOMORPHINE HYDROCHLORIDE

Tunisia (TN)

Turkey (TR)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • APOJECT as APOMORPHINE HYDROCHLORIDE
  • DOPAMOR as APOMORPHINE HYDROCHLORIDE
  • EPAMOR as APOMORPHINE HYDROCHLORIDE
  • PARGYCIL as APOMORPHINE HYDROCHLORIDE
  • PARKOFF as APOMORPHINE HYDROCHLORIDE
  • VERAPOMOR as APOMORPHINE HYDROCHLORIDE

United Kingdom (UK)

  • APO-GO as APOMORPHINE HYDROCHLORIDE
  • DACEPTON as APOMORPHINE HYDROCHLORIDE

United States (US)

  • APOKYN as APOMORPHINE HYDROCHLORIDE
  • KYNMOBI as APOMORPHINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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