Argatroban C₂₃H₃₆N₆O₅S

Active ingredient description

Argatroban, a synthetic L-arginine derivative, is a direct thrombin inhibitor (molecular weight 526.65) that binds reversibly to thrombin. Argatroban exerts its anticoagulant effect independently of antithrombin III and inhibits fibrin formation; activation of coagulation factors V, VIII and XIII; activation of protein C; and platelet aggregation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AE Direct thrombin inhibitors
Discover more medicines within B01AE03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Information Source
Document Type
Medicines & Healthcare Products Regulatory Agency (GB)
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: C₂₃H₃₆N₆O₅S
Molecular mass: 508.64 g/mol

External identifiers

CAS Substance: 74863-84-6
DrugBank Drug: DB00278
PubChem Compound: 92722
RxNorm Ingredient: 15202
SNOMED-CT Concept: 116508003
Argatroban (substance)
UNII Identifier: IY90U61Z3S


Argatroban is an active ingredient of these brands:

Estonia (EE)

Finland (FI)

France (FR)

Japan (JP)

Netherlands (NL)

Romania (RO)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

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