Chemical formula: C₂₃H₃₆N₆O₅S  Molecular mass: 508.64 g/mol  PubChem compound: 92722

Active ingredient description

Argatroban, a synthetic L-arginine derivative, is a direct thrombin inhibitor (molecular weight 526.65) that binds reversibly to thrombin. Argatroban exerts its anticoagulant effect independently of antithrombin III and inhibits fibrin formation; activation of coagulation factors V, VIII and XIII; activation of protein C; and platelet aggregation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
B01AE03 Argatroban B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AE Direct thrombin inhibitors
Discover more medicines within B01AE03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
EXEMBOL Solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 74863-84-6
DrugBank Drug: DB00278
PubChem Compound: 92722
RxNorm Ingredient: 15202
SNOMED-CT Concept: 116508003
Argatroban (substance)
UNII Identifier: IY90U61Z3S


Argatroban is an active ingredient of these brands:

Estonia (EE)

Finland (FI)

France (FR)

Japan (JP)

Netherlands (NL)

Romania (RO)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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