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Argatroban

Description

Argatroban, a synthetic L-arginine derivative, is a direct thrombin inhibitor (molecular weight 526.65) that binds reversibly to thrombin. Argatroban exerts its anticoagulant effect independently of antithrombin III and inhibits fibrin formation; activation of coagulation factors V, VIII and XIII; activation of protein C; and platelet aggregation.

ATC Classification

Code
Title
Category
B01AE03
Argatroban
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AE Direct thrombin inhibitors

Trade names

Trade name
Countries

France Netherlands Spain

United Kingdom

Product Monographs

Monograph
Type
Country
Exembol 100 mg/ml concentrate for solution for infusion
MPI, EU: SmPC
UK
EXEMBOL Solution for infusion
MPI, EU: SmPC
UK