Argatroban

Active ingredient description

Argatroban, a synthetic L-arginine derivative, is a direct thrombin inhibitor (molecular weight 526.65) that binds reversibly to thrombin. Argatroban exerts its anticoagulant effect independently of antithrombin III and inhibits fibrin formation; activation of coagulation factors V, VIII and XIII; activation of protein C; and platelet aggregation.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
B01AE03
Argatroban
B Blood and blood forming organs → B01 Antithrombotic agents → B01A Antithrombotic agents → B01AE Direct thrombin inhibitors
Discover more medicines within B01AE03

Medicines

Argatroban is the active ingredient of these drugs:

Drug
Countries
ARGANOVA

France Netherlands Spain

EXEMBOL

United Kingdom

NOVASTAN

Finland

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
EXEMBOL Solution for infusion
Summary of product characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

IY90U61Z3S - ARGATROBAN

CAS registry number

74863-84-6 - argatroban

SNOMED-CT

116508003 - Argatroban (substance)

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