Arsenic trioxide As₂O₃
Also known as: Arsenic Sesquioxide Arsenic Oxidearsenous Trioxide

Active ingredient description

Arsenic trioxide causes morphological changes and deoxyribonucleic acid (DNA) fragmentation characteristic of apoptosis in NB4 human promyelocytic leukaemia cells in vitro. Arsenic trioxide also causes damage or degradation of the fusion protein PML/RAR alpha.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Arsenic trioxide
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents
Discover more medicines within L01XX27

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
European Medicines Agency (EU)
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Chemical formula: As₂O₃
Molecular mass: 197.84 g/mol

External identifiers

CAS Substance: 1327-53-3
DrugBank Drug: DB01169
KEGG Drug: D02106
PubChem Compound: 14888
RxNorm Ingredient: 18330
SNOMED-CT Concept: 72251000
Arsenic trioxide (substance)
UNII Identifier: S7V92P67HO
ARSENIC TRIOXIDE

Medicines

Arsenic trioxide is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Brazil (BR)

Canada (CA)

Cyprus (CY)

Ecuador (EC)

Estonia (EE)

Finland (FI)

France (FR)

Hong Kong (HK)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Netherlands (NL)

New Zealand (NZ)

Poland (PL)

Romania (RO)

Spain (ES)

Turkey (TR)

United Kingdom (UK)

While we strive to include the brand names of medicines across all countries, our index remains incomplete. Therefore, it is possible that this medicine may also be marketed under different names in other countries.

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