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Arsenic trioxide

Also known as: Arsenic Sesquioxide Arsenic Oxidearsenous Trioxide

Description

Arsenic trioxide causes morphological changes and deoxyribonucleic acid (DNA) fragmentation characteristic of apoptosis in NB4 human promyelocytic leukaemia cells in vitro. Arsenic trioxide also causes damage or degradation of the fusion protein PML/RAR alpha.

ATC Classification

Code
Title
Category
L01XX27
Arsenic trioxide
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01X Other antineoplastic agents → L01XX Other antineoplastic agents

Trade names

Trade name
Countries

Australia

Austria Canada Cyprus Netherlands United States

Product Monographs

Monograph
Type
Country
TRISENOX Concentrate for solution for infusion
MPI, EU: SmPC