Artenimol and Piperaquine

Therapeutic indications

Artenimol and Piperaquine is indicated for:

Plasmodium falciparum malaria

Population group: only infants (40 days - 1 year old) , children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

Eurartesim is indicated for the treatment of uncomplicated Plasmodium falciparum malaria in adults, adolescents, children and infants 6 months and over and weighing 5 kg or more.

Consideration should be given to official guidance on the appropriate use of antimalarial medicinal products, including information on the prevalence of resistance to artenimol/piperaquine in the geographical region where the infection was acquired.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Artenimol and Piperaquine is contraindicated in the following cases:

Pregnancy

Pregnancy

Lactation

Lactation

Severe malaria according to WHO definition

Complicated malaria

Family history of sudden death or of congenital prolongation of the QTc interval

at least one of
Family history of sudden death
Family history of congenital long QT syndrome

Prolongation of the QTc-interval

Risk factors that increase the risk of QT prolongation

History of symptomatic cardiac arrhythmias or with clinically relevant bradycardia

at least one of
Arrhythmia
Bradycardia

Predisposing cardiac conditions for arrhythmia

at least one of
Hypertension
Left ventricular hypertrophy
Hypertrophic cardiomyopathy
Congestive heart failure

Electrolyte disturbances

Disorder of electrolytes

Medicinal products that are known to prolong the QTc interval

Drugs prolonging QT interval

Grapefruit juice

Grapefruit

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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Summary of Product Characteristics (SPC) 2023: EURARTESIM Film-coated tablet
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