Asfotase alfa

Therapeutic indications

Asfotase alfa is indicated for:

Hypophosphatasia

Irrespective of gender only Children (1 year - 12 years old) , Adolescents (12 years - 18 years old) , Adults (18 - 65 years old)

Asfotase alfa is indicated for long-term enzyme replacement therapy in patients with paediatric-onset hypophosphatasia to treat the bone manifestations of the disease.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Subcutaneous - 2 mg/kg 3 times per week

Treatment 2: Subcutaneous - 1 mg/kg 6 times per week

Contraindications

Active ingredient Asfotase alfa is contraindicated in the following cases:

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