Atazanavir C₃₈H₅₂N₆O₇

Therapeutic indications

Atazanavir is indicated for:

HIV-1 infection

Population group: both men and women, only adults (18 - 65 years old)

Atazanavir, co-administered with low dose ritonavir, is indicated for the treatment of HIV-1 infected adults and paediatric patients 6 years of age and older in combination with other antiretroviral medicinal products.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

HIV-1 infection

Population group: both men and women, only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Atazanavir, co-administered with low dose ritonavir, is indicated for the treatment of HIV-1 infected adults and paediatric patients 6 years of age and older in combination with other antiretroviral medicinal products.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Atazanavir is contraindicated in the following cases:

Glecaprevir, pibrentasvir

at least one of
Glecaprevir
Pibrentasvir

Severe hepatic insufficiency

Hepatic failure stage IV

Ritonavir in moderate hepatic insufficiency

Ritonavir and additionally
Hepatic failure stage III

Simvastatin, lovastatin

at least one of
Simvastatin
Lovastatin

Rifampicin

Rifampicin

Sildenafil in pulmonary arterial hypertension (PAH)

Sildenafil

CYP3A4 substrates

CYP3A4 substrates

Grazoprevir, elbasvir, glecaprevir, pibrentasvir

at least one of
Grazoprevir
Elbasvir
Glecaprevir
Pibrentasvir

St. John's wort (Hypericum perforatum)

Hypericum perforatum (St John's Wort)

Quetiapine

Quetiapine

Lurasidone

Lurasidone

Alfuzosin

Alfuzosin

Quinidine

Quinidine

Bepridil

Bepridil

Midazolam, triazolam

at least one of
Midazolam
Triazolam

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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