Atovaquone

Chemical formula: C₂₂H₁₉ClO₃  Molecular mass: 366.837 g/mol  PubChem compound: 74989

Active ingredient description

Atovaquone is a selective and potent inhibitor of the eukaryotic mitochondrial electron transport chain in a number of parasitic protozoa and the parasitic fungus P. jiroveci. The site of action appears to be the cytochrome bc1 complex (complex III).

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
P01AX06
Atovaquone
P Antiparasitic products, insecticides and repellents → P01 Antiprotozoals → P01A Agents against amoebiasis and other protozoal diseases → P01AX Other agents against amoebiasis and other protozoal diseases
Discover more medicines within P01AX06

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title
Information Source
Document Type
 
WELLVONE Oral suspension
Medicines & Healthcare Products Regulatory Agency (GB)
MPI, EU: SmPC
MEPRON Oral suspension
FDA, National Drug Code (US)
MPI, US: SPL/PLR

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 95233-18-4
DrugBank Drug: DB01117
KEGG Drug: D00236
PubChem Compound: 74989
RxNorm Ingredient: 60212
SNOMED-CT Concept: 386899002
Atovaquone (substance)
UNII Identifier: Y883P1Z2LT
ATOVAQUONE

Medicines

Atovaquone is an active ingredient of these brands:

United States (US)

Australia (AU)

Austria (AT)

Canada (CA)

Estonia (EE)

Finland (FI)

France (FR)

Ireland (IE)

Japan (JP)

Lithuania (LT)

Malta (MT)

Netherlands (NL)

New Zealand (NZ)

Nigeria (NG)

Poland (PL)

Singapore (SG)

South Africa (ZA)

Spain (ES)

United Kingdom (UK)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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