Avatrombopag

Active ingredient description

Avatrombopag is an orally active, small molecule thrombopoietin (TPO) receptor agonist that stimulates proliferation and differentiation of megakaryocytes from bone marrow progenitor cells resulting in increased production of platelets. Avatrombopag does not compete with TPO for binding to the TPO receptor and has an additive effect with TPO on platelet production.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
B02BX08
Avatrombopag
B Blood and blood forming organs → B02 Antihemorrhagics → B02B Vitamin K and other hemostatics → B02BX Other systemic hemostatics
Discover more medicines within B02BX08

Medicines

Avatrombopag is the active ingredient of these drugs:

Drug
Countries
DOPTELET

Austria Finland Ireland Lithuania Poland

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
DOPTELET Film-coated tablet
Structured Product Labeling (SPL/PLR)
US
DOPTELET Film-coated tablet
Summary of Product Characteristics (SPC)

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

3H8GSZ4SQL - AVATROMBOPAG

SNOMED-CT

770717002 - Avatrombopag (substance)

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