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Azelastine

Description

Azelastine, a phthalazinone derivative is classified as a potent long-acting anti-allergic compound with selective H1 antagonist properties. An additional anti-inflammatory effect could be detected after topical ocular administration. Data from in vivo (pre-clinical) and in vitro studies show that azelastine inhibits the synthesis or release of the chemical mediators known to be involved in early and late stage allergic reactions e.g. leukotriene, histamine, PAF and serotonin.

ATC Classification

Code
Title
Category
R01AC03
Azelastine
R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AC Antiallergic agents, excl. corticosteroids
R06AX19
Azelastine
R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AX Other antihistamines for systemic use
S01GX07
Azelastine
S Sensory organs → S01 Ophthalmologicals → S01G Decongestants and antiallergics → S01GX Other antiallergics

Trade names

Trade name
Countries

Cyprus Spain

Austria France Netherlands

Austria

Austria

Austria United States

Austria

Austria

Singapore

United Kingdom

Netherlands

United Kingdom

Spain

Trade names (in combination): DYMISTA SYNAZE

Product Monographs

Monograph
Type
Country
Rhinolast Allergy 0.1% w/v Nasal Spray
MPI, EU: SmPC
UK
OPTILAST Eye drops
MPI, EU: SmPC
UK