Azelastine

Active ingredient description

Azelastine, a phthalazinone derivative is classified as a potent long-acting anti-allergic compound with selective H1 antagonist properties. An additional anti-inflammatory effect could be detected after topical ocular administration. Data from in vivo (pre-clinical) and in vitro studies show that azelastine inhibits the synthesis or release of the chemical mediators known to be involved in early and late stage allergic reactions e.g. leukotriene, histamine, PAF and serotonin.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Azelastine
R Respiratory system → R01 Nasal preparations → R01A Decongestants and other nasal preparations for topical use → R01AC Antiallergic agents, excl. corticosteroids
Discover more medicines within R01AC03
Azelastine
R Respiratory system → R06 Antihistamines for systemic use → R06A Antihistamines for systemic use → R06AX Other antihistamines for systemic use
Discover more medicines within R06AX19
Azelastine
S Sensory organs → S01 Ophthalmologicals → S01G Decongestants and antiallergics → S01GX Other antiallergics
Discover more medicines within S01GX07

Medicines

Azelastine is the active ingredient of these drugs:

Drug
Countries

Cyprus Spain

Austria France Lithuania Netherlands Poland

Austria

Austria

Poland

Austria Ireland United States

Tunisia

Austria

Austria

Poland

Hong Kong Singapore

Hong Kong

Brazil

Ireland United Kingdom

Netherlands

Ireland United Kingdom

Brazil

Spain

Azelastine is also found within below combination drugs:

AZECORT , BILENI , DYMISTA , SYNAZE

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of product characteristics (SPC)
UK
Summary of product characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

ZQI909440X - AZELASTINE

CAS registry number

58581-89-8 - azelastine

SNOMED-CT

372520005 - Azelastine (substance)