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Barnidipine

Therapeutic Indications

Barnidipine is indicated for:

Mild to moderate essential hypertension

Irrespective of gender only Adults (18 years old or older)

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Oral - 10-20 mg once daily

Contraindications

Active ingredient Barnidipine is contraindicated in the following cases:

Untreated heart failure

No gender/age discrimination

Hepatic impairment

No gender/age discrimination

Strong CYP3A4 inhibitors

No gender/age discrimination

Blood levels of barnidipine may be increased when used in combination with strong CYP3A4 inhibitors (results in vitro interaction studies). Therefore, antiproteases, ketoconazole, itraconazole, erythromycin and clarithromycin should not be used concomitantly.

Severe renal impairment (creatinine clearance <10 ml/min)

No gender/age discrimination

Unstable angina pectoris, acute myocardial infarction

No gender/age discrimination

Unstable angina pectoris and acute myocardial infarction (in the first 4 weeks).