Belzutifan

Chemical formula: C₁₇H₁₂F₃NO₄S  Molecular mass: 383.044 g/mol  PubChem compound: 117947097

Therapeutic indications

Belzutifan is indicated for:

Von Hippel-Lindau disease

Population group: only adults (18 - 65 years old)

Belzutifan is indicated for treatment of adult patients with von Hippel-Lindau (VHL) disease who require therapy for associated renal cell carcinoma (RCC), central nervous system (CNS) hemangioblastomas, or pancreatic neuroendocrine tumors (pNET), not requiring immediate surgery.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Advanced renal cell carcinoma

Population group: only adults (18 - 65 years old)

Belzutifan is indicated for the treatment of adult patients with advanced renal cell carcinoma (RCC) following a programmed death receptor-1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitor and a vascular endothelial growth factor tyrosine kinase inhibitor (VEGF-TKI).

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Belzutifan is contraindicated in the following cases:

Lactation

Lactation

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