Chemical formula: C₁₆H₂₁Cl₂N₃O₂ Molecular mass: 358.263 g/mol PubChem compound: 65628
Bendamustine is indicated for:
Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)
First-line treatment of chronic lymphocytic leukaemia (Binet stage B or C) in patients for whom fludarabine combination chemotherapy is not appropriate.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Population group: only adolescents (12 years - 18 years old) , adults (18 years old or older)
Indolent non-Hodgkin’s lymphomas as monotherapy in patients who have progressed during or within 6 months following treatment with rituximab or a rituximab containing regimen.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Population group: only adults (18 years old or older)
Front line treatment of multiple myeloma (Durie-Salmon stage II with progress or stage III) in combination with prednisone for patients older than 65 years who are not eligible for autologous stem cell transplantation and who have clinical neuropathy at time of diagnosis precluding the use of thalidomide or bortezomib containing treatment.
For this indication, competent medicine agencies globally authorize below treatments (click for details):
Bendamustine is contraindicated in the following cases:
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