Benperidol

Chemical formula: C₂₂H₂₄FN₃O₂  Molecular mass: 381.451 g/mol  PubChem compound: 16363

Pharmacodynamic properties

Benperidol is a potent neuroleptic of the butyrophenone series with general properties similar to those of haloperidol.

Pharmacokinetic properties

After administration of benperidol (2 mg tablets PO) to volunteers, the following values have been reported:

Cmax 4.1 ± 1.7 µg/l, Tmax 2.9 ± 1.8 h, AUC(0-24) 39.8 ± 9.4 µg.h/l.

After repeated administration of 3 and 12 mg benperidol to patients, plasma levels of 10 and 30 µg/l respectively have been reported.

Preclinical safety data

No further data.

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