Brand names: BESIVANCE
Besifloxacin is a fluoroquinolone antibacterial.
Plasma concentrations of besifloxacin were measured in adult patients with suspected bacterial conjunctivitis who received besifloxacin bilaterally three times a day (16 doses total). Following the first and last dose, the maximum plasma besifloxacin concentration in each patient was less than 1.3 ng/mL. The mean besifloxacin Cmax was 0.37 ng/mL on day 1 and 0.43 ng/mL on day 6. The average elimination half-life of besifloxacin in plasma following multiple dosing was estimated to be 7 hours.