Butamirate

Chemical formula: C₁₈H₂₉NO₃  Molecular mass: 307.434 g/mol 

Active ingredient description

Butamirate (or brospamin) is a cough suppressant. It binds to the cough center in the medulla oblongata, more specifically the dextromethorphan-binding site in guinea pig brain with high affinity.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC Group Classification
R05DB13 Butamirate R Respiratory system → R05 Cough and cold preparations → R05D Cough suppressants, excl. combinations with expectorants → R05DB Other cough suppressants
Discover more medicines within R05DB13

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 BUTAMIRATE Syrup MPI, EU: SmPC European Medicines Agency (EU)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 18109-80-3
CAS Substance: 18109-81-4
DrugBank Drug: DB13731
RxNorm Ingredient: 19862
UNII Identifier: M75MZG2236
BUTAMIRATE

Medicines

Butamirate is an active ingredient of these brands:

Croatia (HR)

Cyprus (CY)

Estonia (EE)

Lithuania (LT)

Malta (MT)

Poland (PL)

Romania (RO)

Tunisia (TN)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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