Leading the way to safer medication
 Crosscheck  Recommender

C1-inhibitor

Also known as: C1 esterase inhibitor C1-inh

Brand names: BERINERT CINRYZE HAEGARDA

Therapeutic Indications

C1-inhibitor is indicated for:

Prevention of angioedema

Irrespective of gender only Children (1 year - 12 years old)

Routine prevention of angioedema attacks in adults, adolescents and children (6 years old and above) with severe and recurrent attacks of hereditary angioedema (HAE), who are intolerant to or insufficiently protected by oral prevention treatments, or patients who are inadequately managed with repeated acute treatment.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 500-1,000 IU once

Hereditary angioedema (HAE)

Irrespective of gender only Children (1 year - 12 years old)

Treatment and pre-procedure prevention of angioedema attacks in adults, adolescents and children (2 years old and above) with hereditary angioedema (HAE).

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 500-1,000 IU once

Prevention of angioedema

Irrespective of gender only Adolescents (12 years - 18 years old) , Adults (18 - 65 years old)

Routine prevention of angioedema attacks in adults, adolescents and children (6 years old and above) with severe and recurrent attacks of hereditary angioedema (HAE), who are intolerant to or insufficiently protected by oral prevention treatments, or patients who are inadequately managed with repeated acute treatment.

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 1,000 IU once

Hereditary angioedema (HAE)

Irrespective of gender only Adolescents (12 years - 18 years old) , Adults (18 - 65 years old)

Treatment and pre-procedure prevention of angioedema attacks in adults, adolescents and children (2 years old and above) with hereditary angioedema (HAE).

For this indication, the medical literature mentions below treatments (click for details):

Treatment 1: Intravenous - 1,000 IU once

Contraindications

Active ingredient C1-inhibitor is contraindicated in the following cases: