Camizestrant

Chemical formula: C₂₄H₂₈F₄N₆  Molecular mass: 476.231 g/mol  PubChem compound: 134453496

Therapeutic indications

Camizestrant is indicated for:

ER-positive, HER2-negative, breast cancer with an ESR1-mutation

Population group: only adults (18 years old or older)

Etcamah in combination with a CDK4/6 inhibitor (palbociclib, ribociclib, or abemaciclib) is indicated for the treatment of adult patients with ER-positive, HER2-negative, locally advanced or metastatic breast cancer upon detection of ESR1-mutation and without disease progression during first-line endocrine therapy in combination with a CDK4/6 inhibitor.

In pre- or peri-menopausal women and in men, camizestrant plus a CDK4/6 inhibitor should be combined with a luteinizing hormone releasing hormone (LHRH) agonist or antagonist.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Camizestrant is contraindicated in the following cases:

Lactation

Lactation

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