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Canagliflozin

Description

Canagliflozin is an orally-active inhibitor of SGLT2. The SGLT2 transporter, expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. By inhibiting SGLT2, canagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose (RTG).

ATC Classification

Code
Title
Category
A10BK02
Canagliflozin
A Alimentary tract and metabolism → A10 Drugs used in diabetes → A10B Blood glucose lowering drugs, excl. insulins → A10BK Sodium-glucose co-transporter 2 (SGLT2) inhibitors

Trade names

Trade name
Countries
INVOKANA

Austria Canada Cyprus Netherlands Singapore

Trade names (in combination): INVOKAMET VOKANAMET

Product Monographs

Monograph
Type
Country
INVOKANA Film-coated tablets
MPI, EU: SmPC

2D Molecule Structure

Unique Ingredient Identifier (UNII)

0SAC974Z85 - CANAGLIFLOZIN

 
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