Capreomycin

Molecular mass: 1,321.412 g/mol  PubChem compound: 3000502

Therapeutic indications

Capreomycin is indicated for:

Active against human strains of Mycobacterium tuberculosis

Population group: only adults (18 years old or older)

Capreomycin is active against human strains of Mycobacterium tuberculosis. Frequent cross-resistance occurs between capreomycin and viomycin. Varying degrees of cross-resistance between capreomycin and kanamycin and neomycin have been reported. No cross-resistance has been observed between capreomycin and isoniazid, aminosalicylic acid, cycloserine, streptomycin, ethionamide or ethambutol. Capreomycin should be used concomitantly with other appropriate antituberculous agents for the treatment of pulmonary infections caused by capreomycin- susceptible strains of Mycobacterium tuberculosis when the primary agents (isoniazid, rifampicin, streptomycinand ethambutol) have been ineffective or cannot be used because of toxicity or the presence of resistant tubercle bacilli. 1

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Capreomycin is contraindicated in the following cases:

Contraindication

at least one of
Pregnancy
Renal failure
Aminoglycoside antibacterials

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