Carbamazepine

Chemical formula: C₁₅H₁₂N₂O  Molecular mass: 236.269 g/mol  PubChem compound: 2554

Therapeutic indications

Carbamazepine is indicated for:

Epilepsy

Population group: only adults (18 years old or older)

Carbamazepine is indicated for generalised tonic-clonic and partial seizures.

Carbamazepine is not usually effective in absences (petit mal) and myoclonic seizures. Moreover, anecdotal evidence suggests that seizure exacerbation may occur in patients with atypical absences.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Epilepsy

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old)

Carbamazepine is indicated for generalised tonic-clonic and partial seizures.

Carbamazepine is not usually effective in absences (petit mal) and myoclonic seizures. Moreover, anecdotal evidence suggests that seizure exacerbation may occur in patients with atypical absences.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Paroxysmal pain of trigeminal neuralgia

Population group: only elderly (65 years old or older)

Carbamazepine is indicated for the paroxysmal pain of trigeminal neuralgia.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Prophylaxis of manic-depressive psychosis

Population group: only adults (18 years old or older)

Carbamazepine is indicated for the prophylaxis of manic-depressive psychosis in patients unresponsive to lithium therapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Paroxysmal pain of trigeminal neuralgia

Population group: only adults (18 - 65 years old)

Carbamazepine is indicated for the paroxysmal pain of trigeminal neuralgia.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Carbamazepine is contraindicated in the following cases:

Atrioventricular block

AVB - Atrioventricular block

Bone marrow depression

Bone marrow depression

Hepatic porphyria

Hepatic porphyria

Acute intermittent porphyria

Acute intermittent porphyria

Monoamine oxidase inhibitors (MAOIs)

Monoamine oxidase inhibitors (MAOIs)

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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