Cefatrizine

Chemical formula: C₁₈H₁₈N₆O₅S₂  Molecular mass: 462.5 g/mol 

Active ingredient description

Cefatrizine is a broad-spectrum, semisynthetic, first-generation cephalosporin with antibacterial activity. Cefatrizine binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J01DB07 Cefatrizine J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01D Other beta-lactam antibacterials → J01DB First-generation cephalosporins
Discover more medicines within J01DB07

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 51627-14-6
DrugBank Drug: DB13266
KEGG Drug: D02406
RxNorm Ingredient: 2179
SNOMED-CT Concept: 96056009
Cefatrizine (substance)
UNII Identifier: 8P4W949T8K
CEFATRIZINE

Medicines

Cefatrizine is an active ingredient of these brands:

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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