Chemical formula: C₁₆H₁₉N₃O₄S Molecular mass: 349.405 g/mol PubChem compound: 38103
As with all medicines, use should be avoided in pregnancy especially in the first trimester, unless considered essential by the physician.
Cefradine is excreted in breast milk and therefore should be used with caution in lactating mothers.
Although animal studies have shown no teratogenic effects, safety in pregnancy has not been established.
Since the medicine may cause dizziness, patients should be cautioned about operating hazardous machinery, including automobiles.
Undesirable effects are uncommon and mainly mild in nature. They are limited essentially to gastrointestinal disturbances and on occasion to hypersensitivity phenomena.
Rarely: Antibiotic-associated colitis
Frequency unknown: Vaginitis, candidal overgrowth, candidiasis
Frequency unknown: Eosinophilia, blood disorders (including thrombocytopenia, leucopenia, agranulocytosis, aplastic anaemia and haemolytic anaemia)
Frequency unknown: Fever, athralgia, serum sickness-like reactions, anaphylaxis
Frequency unknown: Confusion, sleep disturbances
Frequency unknown: Hypersensitivity, hyperactivity, hypertonia, dizziness, nervousness
Rarely: Headache
Frequency unknown: Diarrhoea, nausea, glossitis, heartburn
Rarely: Vomiting, abdominal discomfort,
Frequency unknown: Liver, enzyme disturbances, transient hepatitis, cholestatic jaundice
Frequency unknown: Rashes, toxic epidermal necrolysis, pruritis, urticaria, erythema multiforme, Stevens-Johnson syndrome, oedema
Frequency unknown: Reversible interstitial nephritis
Frequency unknown: Tightness in the chest
Frequency unknown: Elevation of blood urea nitrogen, serum creatinine, alanine aminotransferase, aspartate aminotransferase, total bilirubin, alkaline phosphates, positive direct Coombs' test
Frequency unknown: joint pain
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