Cevimeline

Chemical formula: C₁₀H₁₇NOS  Molecular mass: 199.313 g/mol  PubChem compound: 25137844

Active ingredient description

Cevimeline is a cholinergic agonist which binds to muscarinic receptors. Muscarinic agonists in sufficient dosage can increase secretion of exocrine glands, such as salivary and sweat glands and increase tone of the smooth muscle in the gastrointestinal and urinary tracts.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
N07AX03 N Nervous system → N07 Other nervous system drugs → N07A Parasympathomimetics → N07AX Other parasympathomimetics
Discover more medicines within N07AX03

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
EVOXAC Capsule FDA, National Drug Code (US) MPI, US: SPL/Old

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 107233-08-9
DrugBank Drug: DB00185
KEGG Drug: D00661
PubChem Compound: 25137844
RxNorm Ingredient: 44281
SNOMED-CT Concept: 409284005
Cevimeline (substance)
UNII Identifier: K9V0CDQ56E
CEVIMELINE

Medicines

Cevimeline is an active ingredient of these brands:

United States (US)

  • EVOXAC as CEVIMELINE HYDROCHLORIDE

Japan (JP)

  • EVOXAC as CEVIMELINE HYDROCHLORIDE
  • SALIGREN as CEVIMELINE HYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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