Chemical formula: C₁₁H₁₂Cl₂N₂O₅ Molecular mass: 323.129 g/mol PubChem compound: 5959
Chloramphenicol is a broad spectrum antibiotic which has activity against many types of Gram-positive and Gram-negative bacteria. It acts by interfering with bacterial protein synthesis. Chloramphenicol is widely distributed in body tissues and fluids and enters the cerebrospinal fluid.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D06AX02 | Chloramphenicol | D Dermatologicals → D06 Antibiotics and chemotherapeutics for dermatological use → D06A Antibiotics for topical use → D06AX Other antibiotics for topical use |
| D10AF03 | Chloramphenicol | D Dermatologicals → D10 Anti-acne preparations → D10A Anti-acne preparations for topical use → D10AF Antiinfectives for treatment of acne |
| G01AA05 | Chloramphenicol | G Genito urinary system and sex hormones → G01 Gynecological antiinfectives and antiseptics → G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS → G01AA Antibiotics |
| J01BA01 | Chloramphenicol | J Antiinfectives for systemic use → J01 Antibacterials for systemic use → J01B Amphenicols → J01BA Amphenicols |
| S01AA01 | Chloramphenicol | S Sensory organs → S01 Ophthalmologicals → S01A Antiinfectives → S01AA Antibiotics |
| S02AA01 | Chloramphenicol | S Sensory organs → S02 Otologicals → S02A Antiinfectives → S02AA Antiinfectives |
| S03AA08 | Chloramphenicol | S Sensory organs → S03 Ophthalmological and otological preparations → S03A Antiinfectives → S03AA Antiinfectives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CLOROGEN Eye drops, solution | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| Kemicetine Succinate Injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| CHLORAMPHENICOL 1.0% Eye ointment | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Chloramphenicol is an active ingredient of these brands:
Australia (AU)Austria (AT)Brazil (BR)
Cyprus (CY)
Ecuador (EC)Estonia (EE)
Hong Kong (HK)
Ireland (IE)Israel (IL)
Japan (JP)
Malta (MT)Mexico (MX)
New Zealand (NZ)Nigeria (NG)
Poland (PL)Romania (RO)
South Africa (ZA)
Turkey (TR)United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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