Chlormethine
Also known as: Embikhin Mustine Mechlorethamine HN2
Brand names: VALCHLOR
Description
Chlormethine is a bifunctional alkylating agent that inhibits rapidly proliferating cells. It works by binding to DNA, crosslinking two strands and preventing cell duplication. It binds to the N7 nitrogen on the DNA base guanine. It has been derivatized into the estrogen analogue estramustine phosphate, used to treat prostate cancer.
ATC Classification
Code
Title
Category
Related medicines
2D Molecule Structure
Unique Ingredient Identifier (UNII)
50D9XSG0VR - MECHLORETHAMINE
CAS Registry Number
51-75-2 - chlormethine
SNOMED-CT
372692002 - Chlormethine (substance)