Choline salicylate

Salicylates and Acetylsalicylic acid: low doses (up to 100 mg/day): Clinical studies indicate that doses up to 100 mg/day for restricted obstetrical use, which require specialised monitoring, appear safe.

Low quantities of salicylates and of their metabolites are excreted into the breast milk. Since adverse effects for the infant have not been reported up to now, short-term use of the recommended dose does not require suspending breastfeeding.

Fertility

There is no information on the effects of topical oral choline salicylate and fertility.

None known.

The list of the following adverse effects relates to those experienced with topical oral salicylates at OTC doses, in short-term use. In the treatment of chronic conditions, under long-term treatment, additional adverse effects may occur. Adverse events which have been associated with salicylates are given below, listed by system organ class and frequency. Frequencies are defined as: very common (≥1/10), common (≥1/100 and <1/10), uncommon (≥1/1000 and <1/100), rare (≥1/10,000 and <1/1000), very rare (<1/10,000) and not known (cannot be estimated from the available data). Within each frequency grouping, adverse events are presented in order of decreasing seriousness.

Respiratory, Thoracic and Mediastinal Disorders

Not known: Bronchospasm, and asthma¹.

Immune System Disorders

Not known: Hypersensitivity

¹ Salicylates may precipitate bronchospasm and induce asthma attacks in susceptible patients.