Cidofovir

Chemical formula: C₈H₁₄N₃O₆P  Molecular mass: 279.187 g/mol  PubChem compound: 60613

Active ingredient description

Cidofovir suppresses HCMV replication by selective inhibition of viral DNA synthesis. Biochemical data support selective inhibition of HSV-1, HSV-2 and HCMV DNA polymerases by cidofovir diphosphate, the active intracellular metabolite of cidofovir.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J05AB12 Cidofovir J Antiinfectives for systemic use → J05 Antivirals for systemic use → J05A Direct acting antivirals → J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
Discover more medicines within J05AB12

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
VISTIDE Concentrate for solution for infusion Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 113852-37-2
DrugBank Drug: DB00369
PubChem Compound: 60613
RxNorm Ingredient: 83171
SNOMED-CT Concept: 386894007
Cidofovir (substance)
UNII Identifier: JIL713Q00N
CIDOFOVIR

Medicines

Cidofovir is an active ingredient of these brands:

Estonia (EE)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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