Chemical formula: C₂₁H₂₆ClNO Molecular mass: 343.89 g/mol PubChem compound: 26987
Clemastine should not be given during pregnancy.
Clemastine should not be given during breast-feeding.
Clemastine has moderate influence on the ability to drive and use machines, due to the antihistamine sedative effect of clemastine, however, patients should be warned not to take charge of vehicles or machinery until the effect of clemastine treatment on the individual is known.
Adverse reactions are listed below, by system organ class and frequency. Frequencies are defined as: very common (≥1/10); common (≥1/100, <1/10); uncommon (≥1/1,000, <1/100); rare (≥1/10,000, <1/1,000) very rare (<1/10,000) or not known (can not to beestimated from available data). Adverse reactions identified during post-marketing use are reported voluntarily from a population of uncertain size, the frequency of these reactions is not known but likely to be rare or very rare.
| MedDRA SOC | Adverse Reaction | Frequency |
|---|---|---|
| Immune system disorders | Anaphylactic shock | Rare |
| Hypersensitivity reactions | Rare | |
| Psychiatric disorders | Excitability, especially in children | Rare |
| Nervous system disorders | Sedation | Common |
| Dizziness | Uncommon | |
| Headache | Rare | |
| Fatigue | Common | |
| Cardiac disorder | Tachycardia | Very rare |
| Palpitations | Very rare | |
| Respiratory, thoracic and mediastinal disorders | Dyspnoea | Rare |
| Gastrointestinal disorder | Abdominal pain | Rare |
| Nausea | Rare | |
| Dry mouth | Rare | |
| Constipation | Very rare | |
| Skin and subcutaneous tissue disorders | Skin rash | Rare |
| General system disorders | Asthenia | Rare |
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