Colchicine

Active ingredient description

Colchicine is considered to act against the inflammatory response to urate crystals, by possibly inhibiting the migration of granulocytes into the inflamed area. Other properties of colchicine, such as interaction with the microtubules, could also contribute to the operation. Onset of action is approximately 12 hours after oral administration and is maximal after 1 to 2 days.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code
Group title
Classification
Colchicine derivatives
L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01C Plant alkaloids and other natural products
Discover more medicines within L01CC
Colchicine
M Musculo-skeletal system → M04 Antigout preparations → M04A Antigout preparations → M04AC Preparations with no effect on uric acid metabolism
Discover more medicines within M04AC01

Medicines

Colchicine is the active ingredient of these drugs:

Drug
Countries

Brazil

Brazil

Poland

Hong Kong

Hong Kong

Singapore

United States

Austria

Australia Hong Kong New Zealand

Finland

United States

Brazil

Hong Kong

Australia

United States

Hong Kong

Colchicine is also found within below combination drugs:

COLCHIMAX

Product monographs

Medicine agencies around the world have authorized marketing of this active ingredient according to these medication package inserts (MPIs):

Title
Type
Country
Summary of Product Characteristics (SPC)
UK

Structural formula

Graphic representation of the active ingredient's molecular structure

Unique ingredient identifier (UNII)

SML2Y3J35T - COLCHICINE

CAS registry number

64-86-8 - Colchicine

SNOMED-CT

387413002 - Colchicine (substance)