Colesevelam

Chemical formula: C₃₁H₆₇Cl₃N₄O  Molecular mass: 616.438 g/mol 

Therapeutic indications

Colesevelam is indicated for:

Primary hypercholesterolaemia

Population group: only adults (18 years old or older)

Colesevelam co-administered with a 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase inhibitor (statin) is indicated as adjunctive therapy to diet to provide an additive reduction in low-density lipoprotein cholesterol (LDL-C) levels in adult patients with primary hypercholesterolaemia who are not adequately controlled with a statin alone.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Colesevelam is contraindicated in the following cases:

Bowel obstruction, biliary obstruction

at least one of
Intestinal obstruction
Obstruction of biliary tree

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