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Crofelemer

Description

Crofelemer is an inhibitor of both the cyclic adenosine monophosphate (cAMP)-stimulated cystic fibrosis transmembrane conductance regulator (CFTR) chloride ion (Cl¯) channel, and the calcium-activated Cl¯ channels (CaCC) at the luminal membrane of enterocytes.

ATC Classification

Code
Title
Category
A07XA06
Crofelemer
A Alimentary tract and metabolism → A07 Antidiarrheals, intestinal antiinflammatory/antiinfective agents → A07X Other antidiarrheals → A07XA Other antidiarrheals

Trade names

Trade name
Countries

United States

Product Monographs

Monograph
Type
Country
MYTESI Delayed-release tablet
MPI, US: SPL/PLR
US