Chemical formula: C₇H₁₅Cl₂N₂O₂P Molecular mass: 261.086 g/mol PubChem compound: 2907
Cyclophosphamide has been demonstrated to have a cytostatic effect in many tumour types. The active metabolites of cyclophosphamide are alkylating agents which transfer alkyl groups to DNA during the process of cell division, thus preventing normal synthesis of DNA.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| L01AA01 | Cyclophosphamide | L Antineoplastic and immunomodulating agents → L01 Antineoplastic agents → L01A Alkylating agents → L01AA Nitrogen mustard analogues |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| CYCLOPHOSPHAMIDE Powder for solution for injection/infusion | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC | |
| CYCLOPHOSPHAMIDE Coated Tablet | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Cyclophosphamide is an active ingredient of these brands:
Australia (AU)
Austria (AT)
Brazil (BR)
Canada (CA)Croatia (HR)
Cyprus (CY)
Estonia (EE)
Finland (FI)France (FR)
Germany (DE)
Ireland (IE)Israel (IL)
Japan (JP)
Lithuania (LT)
Mexico (MX)Netherlands (NL)
New Zealand (NZ)
Romania (RO)
South Africa (ZA)
Spain (ES)Tunisia (TN)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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