Cycloserine

Chemical formula: C₃H₆N₂O₂  Molecular mass: 102.092 g/mol  PubChem compound: 6234

Active ingredient description

Cycloserine is an analog of the amino acid D-alanine. It interferes with an early step in bacterial cell wall synthesis in the cytoplasm by competitive inhibition of two enzymes, L-alanine racemase, which forms D-alanine from L-alanine, and D-alanylalanine synthetase, which incorporates D-alanine into the pentapeptide necessary for peptidoglycan formation and bacterial cell wall synthesis.

Medicine classification

This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:

ATC code Group title Classification
J04AB01 Cycloserine J Antiinfectives for systemic use → J04 Antimycobacterials → J04A Drugs for treatment of tuberculosis → J04AB Antibiotics
Discover more medicines within J04AB01

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Title Information Source Document Type  
CYCLOSERINE Capsules Medicines & Healthcare Products Regulatory Agency (GB) MPI, EU: SmPC

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

CAS Substance: 68-41-7
DrugBank Drug: DB00260
PubChem Compound: 6234
RxNorm Ingredient: 3007
SNOMED-CT Concept: 387282000
Cycloserine (substance)
UNII Identifier: 95IK5KI84Z
CYCLOSERINE

Medicines

Cycloserine is an active ingredient of these brands:

United States (US)

Estonia (EE)

Turkey (TR)

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

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