Dabrafenib

Chemical formula: C₂₃H₂₀F₃N₅O₂S₂  Molecular mass: 519.562 g/mol  PubChem compound: 44462760

Therapeutic indications

Dabrafenib is indicated for:

Melanoma with a BRAF V600 mutation

Population group: only adults (18 years old or older)

Melanoma

Dabrafenib as monotherapy or in combination with trametinib is indicated for the treatment of adult patients with unresectable or metastatic melanoma with a BRAF V600 mutation.

Adjuvant treatment of melanoma

Dabrafenib in combination with trametinib is indicated for the adjuvant treatment of adult patients with Stage III melanoma with a BRAF V600 mutation, following complete resection.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Non-small cell lung cancer (NSCLC) with a BRAF V600 mutation

Population group: only adults (18 years old or older)

Dabrafenib in combination with trametinib is indicated for the treatment of adult patients with advanced non-small cell lung cancer with a BRAF V600 mutation.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

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