Daunorubicin

Chemical formula: C₂₇H₂₉NO₁₀  Molecular mass: 527.52 g/mol  PubChem compound: 30323

Therapeutic indications

Daunorubicin is indicated for:

Acute lymphocytic leukaemia

Population group: only children (1 year - 12 years old) , adolescents (12 years - 18 years old) , adults (18 years old or older)

As an antimitotic and cytotoxic for the induction of remissions in acute lymphocytic and myelogenous leukaemias.

Daunorubicin, as part of combination regimen, is indicated for the treatment of acute lymphocytic leukemia and acute myeloid leukemia in children.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Daunorubicin is contraindicated in the following cases:

Prior treatment with maximum cumulative doses of other anthracycline

Anthracyclines and related substances

Lactation

Lactation

Acute infections

Infectious disease

Uncontrolled coronary insufficiency

at least one of
Acute coronary insufficiency
Chronic myocardial ischemia
Impaired left ventricular function

Marrow depression

Bone marrow depression

Oropharyngeal ulceration

Ulcer of pharynx

Chicken pox, herpes zoster

at least one of
Varicella
Herpes zoster

Live attenuated vaccines

Live organism vaccines

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