Decitabine Other names: Dezocitidine

Chemical formula: C₈H₁₂N₄O₄ Molecular mass: 228.205 g/mol PubChem compound: 451668

Therapeutic indications

Decitabine is indicated for:

Acute myeloid leukaemia

Population group: only adults (18 years old or older)

Decitabine is indicated for the treatment of adult patients with newly diagnosed de novo or secondary acute myeloid leukaemia (AML), according to the World Health Organisation (WHO) classification, who are not candidates for standard induction chemotherapy.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

20 mg/m² body surface area by intravenous infusion over 1 hour repeated daily for 5 consecutive days, every 4 weeks and for at least 4 cycles

Contraindications

Decitabine is contraindicated in the following cases:

Lactation

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