Denosumab

Therapeutic indications

Denosumab is indicated for:

Osteoporosis

Population group: only adults (18 years old or older)

Treatment of osteoporosis in postmenopausal women and in men at increased risk of fractures. In postmenopausal women denosumab significantly reduces the risk of vertebral, non-vertebral and hip fractures.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Fractures and prostate cancer

Population group: men, only adults (18 years old or older)

Treatment of bone loss associated with hormone ablation in men with prostate cancer at increased risk of fractures. In men with prostate cancer receiving hormone ablation, denosumab significantly reduces the risk of vertebral fractures.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Fractures and glucocorticoid

Population group: only adults (18 years old or older)

Treatment of bone loss associated with long-term systemic glucocorticoid therapy in adult patients at increased risk of fracture.

For this indication, competent medicine agencies globally authorize below treatments (click for details):

Contraindications

Denosumab is contraindicated in the following cases:

Hypocalcaemia

Hypocalcemia

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Factors such as age, gender, and health history are evaluated to create a personalized medication regimen.

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