Chemical formula: C₁₄H₁₀O₃ Molecular mass: 226.231 g/mol PubChem compound: 2202
Dithranol has been used in the treatment of sub-acute and chronic psoriasis for over 70 years and, during that time it has become established as a safe and effective form of therapy. Its precise mode of action is still to be confirmed, although it has been shown to inhibit DNA replication, cellular respiration and key cellular enzymes eg glucose-6-phosphate dehydrogenase.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| D05AC01 | Other antipsoriatics for topical use | D Dermatologicals → D05 Antipsoriatics → D05A Antipsoriatics for topical use → D05AC Antracen derivatives |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| DITHROCREAM Cream | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Dithranol is an active ingredient of these brands:
Estonia (EE)Ireland (IE)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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