Dordaviprone

Chemical formula: C₂₄H₂₆N₄O  Molecular mass: 386.211 g/mol  PubChem compound: 73777259

Active ingredient description

Dordaviprone is a protease activator of the mitochondrial caseinolytic protease P (ClpP). Dordaviprone also inhibits the dopamine D2 receptor. Dordaviprone exhibited antitumor activity in cell-based assays and in vivo models of H3 K27M-mutant diffuse glioma.

Product monographs

Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):

Document Type Information Source  
 MODEYSO Capsule MPI, US: SPL/PLR FDA, National Drug Code (US)

Structural formula

Graphic representation of the active ingredient's molecular structure

External identifiers

DrugBank Drug: DB14844
KEGG Drug: D12733
PubChem Compound: 73777259
UNII Identifier: 9U35A31JAI
DORDAVIPRONE

Medicines

Dordaviprone is an active ingredient of these brands:

United States (US)

  • MODEYSO as DORDAVIPRONE DIHYDROCHLORIDE

Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide.

 
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