Chemical formula: C₂₄H₃₀N₂O₂ Molecular mass: 378.507 g/mol PubChem compound: 3156
Doxapram is an analeptic agent (a stimulant of the central nervous system). Doxapram produces respiratory stimulation mediated through the peripheral carotid chemoreceptors. It is thought to stimulate the carotid body by inhibiting certain potassium channels. Used as temporary measure in hospitalized patients with acute respiratory insufficiency superimposed on chronic obstructive pulmonary disease.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| R07AB01 | Doxapram | R Respiratory system → R07 Other respiratory system products → R07A Other respiratory system products → R07AB Respiratory stimulants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| DOPRAM Sterile solution for injection | Medicines & Healthcare Products Regulatory Agency (GB) | MPI, EU: SmPC |
Doxapram is an active ingredient of these brands:
United States (US)
France (FR)
Japan (JP)
Malta (MT)
Netherlands (NL)
Romania (RO)
Turkey (TR)
United Kingdom (UK)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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