Chemical formula: C₁₈H₁₉NOS Molecular mass: 297.415 g/mol PubChem compound: 60835
Duloxetine is a combined serotonin (5-HT) and noradrenaline (NA) reuptake inhibitor. It weakly inhibits dopamine reuptake with no significant affinity for histaminergic, dopaminergic, cholinergic and adrenergic receptors.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| N06AX21 | Duloxetine | N Nervous system → N06 Psychoanaleptics → N06A Antidepressants → N06AX Other antidepressants |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| YENTREVE Hard gastro-resistant capsule | European Medicines Agency (EU) | MPI, EU: SmPC | |
| CYMBALTA Hard gastro-resistant capsule | European Medicines Agency (EU) | MPI, EU: SmPC |
Duloxetine is an active ingredient of these brands:
United States (US)
Austria (AT)Brazil (BR)
Canada (CA)
Croatia (HR)Cyprus (CY)Ecuador (EC)Estonia (EE)
Finland (FI)Germany (DE)
Hong Kong (HK)
Ireland (IE)Italy (IT)Japan (JP)
Lithuania (LT)
Malta (MT)
Mexico (MX)
Poland (PL)
Romania (RO)Singapore (SG)
South Africa (ZA)Spain (ES)Turkey (TR)
United Kingdom (UK)Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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