Chemical formula: C₆₅H₈₉GaN₁₄O₁₈S₂ Molecular mass: 1,486.55 g/mol
Gallium ⁶⁸Ga edotreotide binds to somatostatin receptors, with highest affinity (Ki = 2.5 ± 0.5 nanomolar) for subtype 2 receptors (sstr2). Gallium ⁶⁸Ga edotreotide binds to cells that express somatostatin receptors including malignant neuroendocrine cells, which overexpress sstr2 receptors.
This medicinal substance has been classified in the anatomical therapeutic chemical (ATC) classification according to its main therapeutic use as follows:
| ATC code | Group title | Classification |
|---|---|---|
| V09IX09 | V Various → V09 Diagnostic radiopharmaceuticals → V09I Tumour detection → V09IX Other diagnostic radiopharmaceuticals for tumour detection | |
Competent medicine agencies globally have authorized commercialization of this active ingredient according to these medication package inserts (MPIs):
| Title | Information Source | Document Type | |
|---|---|---|---|
| Ga-68-DOTATOC Solution for injection | FDA, National Drug Code (US) | MPI, US: SPL/PLR |
Gallium ⁶⁸Ga edotreotide is an active ingredient of these brands:
United States (US)Austria (AT)
Croatia (HR)
Estonia (EE)
France (FR)
Ireland (IE)
Italy (IT)
Lithuania (LT)
Poland (PL)
Spain (ES)
Note the following: The list of brand names is continuously updated, and thus does not include the total of products circulating worldwide. |
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